Menthol flavoring results in increased particle…
Menthol flavoring results in increased particle pollution and lung damage from e-cigarettes Chandra, D., Bogdanoff, R.F., Bowler, R.P. et al. Electronic cigarette menthol flavoring is associated with increased inhaled micro and sub-micron particles and worse lung function in combustion cigarette smokers. Respir Res. 2023. 24, 108. https://doi.org/10.1186/s12931-023-02410-9
“… we first performed preclinical studies using our novel robotic platform Human Vaping Mimetic Real-Time Particle Analyzer (HUMITIPAA). HUMITIPAA generates fresh aerosols for any desired (electronic cigarette) EC in a very controlled and user-definable manner and utilizes an optical sensing system to quantitate and analyze sub-micron and microparticles from every puff over the course of vaping session in real-time while emulating clinically relevant breathing mechanics and vaping topography. We discovered that addition of menthol flavoring to freshly prepared e-liquid base propylene glycol–vegetable glycerin leads to enhanced particle counts in all tested size fractions, similar to the effect of adding vitamin E acetate to e-liquid we previously reported. Similarly, we found that menthol vs. non-menthol (tobacco) flavored pods from commercially available ECs leads to generation of significantly higher quantities of 1–10 µm particles upon inhalation….
https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-023-02410-9#citeas
Importantly, here we demonstrate utility of the Human Vaping Mimetic Real-Time Particle Analyzer as a predictive enabling technology to identify inhalation toxicological potential of emerging ECs as the chemical formulation of e-liquid gets modified.”
Stephen Hamann
