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Smoking Cessation and Short- and Longer-Term Mortality.

Cho ER, et al. Smoking Cessation and Short- and Longer-Term Mortality. NEJM Evidence. Published February 8, 2024

“Among 1.48 million adults followed for 15 years, 122,697 deaths occurred. Adjusting for age, education, alcohol use, and obesity, current smokers had higher hazard ratios for death compared with never smokers (2.8 for women, 2.7 for men). Survival between 40 and 79 years of age was 12 and 13 years less in women and men, respectively, who smoked compared with never smokers (about 24 to 26 years of life lost for smokers who died from smoking combined with zero loss for smokers who did not die from smoking). Former smokers showed lower hazard ratios (1.3 in both women and men).”

DOI: 10.1056/EVIDoa2300272
https://evidence.nejm.org/doi/full/10.1056/EVIDoa2300272

Comment from results: “Cessation at every age was associated with longer survival, particularly cessation before 40 years of age. Among all ages and compared with continued smoking, cessation of fewer than 3 years potentially averted 5 years of life lost and cessation for 10 or more years averted about 10 years of life lost, yielding survival similar to that of never smokers.”

Stephen Hamann

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