E-cigarettes as a therapeutic intervention for smoking cessation may lead …
E-cigarettes as a therapeutic intervention for smoking cessation may lead to permanent nicotine dependence. Hanewinkel R, Niederberger K, Pedersen A, et al. E-cigarettes and nicotine abstinence: a meta-analysis of randomized controlled trials.
European Respiratory Review 2022 31: 210215 | “We included four RCTs [randomized controlled trials] representing 1598 adult participants (51.0% females)… Compared to NRT [nicotine replacement therapy], e-cigarette use was associated with lower nicotine abstinence rates at the longest follow-up (risk ratio 0.50 (95% CI 0.32–0.77)). Among successful cigarette quitters, the risk of allocated product use by the end of the observational time was higher for e-cigarette users compared to NRT (risk ratio 8.94 (95% CI 3.98–20.07)).” https://err.ersjournals.com/content/31/163/210215 https://err.ersjournals.com/content/errev/31/163/210215.full.pdf
Stephen Hamann
