Juul (and, likely, other fourth generation e-cigarettes) …
Two new papers strongly suggest that Juul (and, likely, other fourth generation e-cigarettes) are more dangerous than earlier tank systems. One, Differential Toxicity of Electronic Cigarette Aerosols Generated from Different Generations of Devices In Vitro and In Vivo (1), finds that Juul has higher pulmonary toxicity than earlier tank systems and the second, Nicotine Formulation Influences the Autonomic and Arrhythmogenic Effects of Electronic Cigarettes (2), finds that breathing e-cigarette aerosols of nicotine salts interferes with nervous system control of the heart and causes potentially dangerous arrhythmias (irregular heart rhythm). Note: This information was posted in Stanton Glantz blog, 11 Dec. 2023
See references:
1 Ma T, et al. Differential Toxicity of Electronic Cigarette Aerosols Generated from Different Generations of Devices In Vitro and In Vivo. Environ. Health 2023, 1, 5, 315–323. Publication Date: September 6, 2023. https://doi.org/10.1021/envhealth.3c00099
2 Kucera C, et al. Nicotine Formulation Influences the Autonomic and Arrhythmogenic Effects of Electronic Cigarettes, Nicotine & Tobacco Research, 27 Nov 2023;, ntad237. https://doi.org/10.1093/ntr/ntad237
Stephen Hamann
