E-cigarettes reduce neutrophil function, important in COPD development

Jasper AE, Faniyi AA, Davis LC, et al. E-cigarette vapor renders neutrophils dysfunctional due to filamentous actin accumulation. Journal of Allergy and Clinical Immunology. Available online 5 September 2023.ISSN 0091-6749; “Neutrophils are central to the pathogenesis of COPD, with changes in phenotype and function implicated in tissue damage…. The significant reduction in effector neutrophil functions after exposure to high-power e-cigarette devices, even in the absence of nicotine, is associated with excessive F-actin polymerisation. This highlights the potentially damaging impact of vaping on respiratory health and reinforces the urgency of research to uncover the long-term health implications of e-cigarettes.”

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Stephen Hamann

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