E-cigarette constituents induce cardiac arrhythmias
Carll AP, Arab C, Salatinit R, et al. E-cigarettes and their lone constituents induce cardiac arrhythmia and conduction defects in mice. Nature Communications. 25 Oct 2022. Volume 13, Article number: 6088. In this animal study, “researchers tested the cardiac impacts of inhaled e-cigarette aerosols solely from the main two ingredients in e-liquids (nicotine-free propylene glycol and vegetable glycerin) or from flavored retail e-liquids containing nicotine. They found that for all e-cigarette aerosols, the animals’ heart rates slowed during puff exposures and sped up afterward as heart rate variability declined, indicating fight-or-flight stress responses. In addition, e-cigarette puffs from a menthol-flavored e-liquid or from propylene glycol alone caused ventricular arrhythmias and other conduction irregularities in the heart.”
https://www.nature.com/articles/s41467-022-33203-1
Authors state, “The findings of this study are important because they provide fresh evidence that the use of e-cigarettes could interfere with normal heart rhythms—something we did not know before…. This is highly concerning given the rapid growth of e-cigarette use, particularly among young people.”
Comment: Heart arrhythmias due to typical e-cigarette aerosol exposures show that e-cigarettes without vitamin E acetate can produce detrimental effects with immediate and long-term consequences.
S. Hamann
