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E-cigarette aerosols from nicotine-salt-containing e-liquids…

E-cigarette aerosols from nicotine-salt-containing e-liquids increase cardiovascular risks Kucera C, et al. Nicotine Formulation Influences the Autonomic and Arrhythmogenic Effects of Electronic Cigarettes. Nicotine & Tobacco Research. 27 Nov 2023. https://doi.org/10.1093/ntr/ntad237

“Our findings suggest that inhalation of e-cig aerosols from nicotine-salt-containing e-liquids could increase the cardiovascular risks of vaping by inducing sympathetic dominance and cardiac arrhythmias.

Exposure to e-cig aerosols containing commercially relevant concentrations of nicotine salts may increase nicotine delivery and impair cardiac function by eliciting β1-adrenoceptor-mediated sympathoexcitation and provoking ventricular arrhythmias. If confirmed in humans, our work suggests that regulatory targeting of nicotine salts through minimum pH standards or limits on acid additives in e-liquids may mitigate the public health risks of vaping.”

https://academic.oup.com/ntr/advance-article-abstract/doi/10.1093/ntr/ntad237/7452838

Stephen Hamann

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