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Maternal smoking status during pregnancy and low birth weight in offspring

Maternal smoking status during pregnancy and low birth weight in offspring: systematic review and meta-analysis Di H, Gan Y, Lu K, et al. Maternal smoking status during pregnancy and low birth weight in offspring: systematic review and meta-analysis of 55 cohort studies published from 1986 to 2020. World J Pediatr. 2022 Jan 28. Online ahead of print. “Maternal smoking during pregnancy was significantly associated with the risk of LBW [low birth weight] in offspring (OR = 1.89, 95% CI = 1.80-1.98). Furthermore, an obvious dose-response relationship between the amount of cigarettes daily smoked in pregnancy and the risk of LBW in offspring was observed. The results of subgroup analyses indicated that the risk of maternal smoking on LBW was larger in more recently conducted studies (P = 0.020) and a longer period of active smoking during pregnancy (P = 0.002) … The risk of maternal smoking on infant LBW seems to be increasing over time and was higher with longer smoking duration throughout pregnancy and more cigarettes smoked daily.” https://link.springer.com/article/10.1007%2Fs12519-021-00501-5

Stephen Hamann

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