Pulmonary host defense altered by chronic e-cigarette use
Davis ES, Ghosh A, Coakley RD, et al. Chronic E-Cigarette Exposure Alters Human Alveolar Macrophage Morphology and Gene Expression. Nicotine & Tobacco Research, ntab186. 14 Sept 2021. Researchers “recruited never-smokers, smokers, and e-cigarette users (vapers) and performed research bronchoscopies to isolate AMs (alveolar macrophages) from bronchoalveolar lavage fluid (BALF) samples and epithelial cells from bronchial brushings. We then performed morphological analyses and used the Nanostring platform to look for changes in gene expression.” https://academic.oup.com/ntr/advance-article-abstract/doi/10.1093/ntr/ntab186/6370121?redirectedFrom=fulltext
“Findings indicate that vaping causes unique changes to AMs and bronchial epithelia compared to non-smokers and smokers which may impact pulmonary host defense.”
Stephen Hamann
