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Past smoking is a variable of importance in cardiovascular risk estimation

Duncan MS, Greevy RA, Tindle HA, et al. Inclusion of Smoking Data in Cardiovascular Disease Risk Estimation. JAMA Cardiol. Published online December 8, 2021. https://jamanetwork.com/journals/jamacardiology/fullarticle/2786611

This study asked if “including former smoking status, pack-years, and years since quitting smoking improved atherosclerotic cardiovascular disease (ASCVD) risk prediction?” Modeling showed that incident ASCVD (myocardial infarction, fatal/nonfatal ischemic stroke, coronary heart disease death) was associated with past smoking although those in this cohort were not current smokers.

“Former smoking, pack-years, and years since quitting significantly improved ASCVD risk prediction in this sample. The Framingham Heart Study offspring cohort is largely composed of non-Hispanic White participants of European ancestry. If results are validated in cohorts of race and ethnicity groups other than White, these variables could be considered for inclusion in future ASCVD risk prediction models.”

Comment: The relationship of past smoking to cardiovascular and other diseases is often overlooked through data that only looks at current smoking as relevant to risk.

S.Hamann

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