Electronic Cigarette Use and the Risk of Cardiovascular Diseases.
Espinoza-Derout J, Shao XM, Lao CJ, et al. Review. Electronic Cigarette Use and the Risk of Cardiovascular Diseases. Front. Cardiovasc. Med., 07 April 2022 | “Several in vitro and in vivo studies delineating the mechanisms of the impact of e-cigarettes on the cardiovascular system have been published. These include mechanisms associated with nicotine or other components of the aerosol or thermal degradation products of e-cigarettes. The increased hyperlipidemia, sympathetic dominance, endothelial dysfunction, DNA damage, and macrophage activation are prominent effects of e-cigarettes. Additionally, oxidative stress and inflammation are unifying mechanisms at many levels of the cardiovascular impairment induced by e-cigarette exposure. This review outlines the contribution of e-cigarettes in the development of cardiovascular diseases and their molecular underpinnings.” https://www.frontiersin.org/articles/10.3389/fcvm.2022.879726/full
Stephen Hamann