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Effects of mango and mint pod-based e-cigarette aerosol inhalation…

Moshensky A, Brand CS, Alhaddad H, et al. Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice. eLife 2022;11:e67621 Authors show that daily exposure to JUUL aerosols increases the expression of genes encoding inflammatory molecules in the brain, lung, heart, and colon of mice. In the experiments, mice were exposed to JUUL mint and JUUL mango-flavored aerosols for 20 minutes, 3 times a day, and for 4 and 12 weeks. The changes in inflammatory gene expression varied depending on the flavor. This suggests that the flavorings themselves contribute to the observed changes. https://elifesciences.org/articles/67621#digest

E-cigarette aerosols increased inflammatory signals in the lungs, brain, heart, and colon of mice. The findings suggest that daily use of pod-based e-cigarettes or e-cigarettes containing high levels of nicotinic salts over months to years may cause inflammation in various organs, increasing the risk of disease and poor health.

Stephen Hamann

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