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E-cigarettes have multiple cardiovascular consequences

Mears MJ, Hookfin HL, Bandaru P, et al. Electronic Nicotine Delivery Systems and Cardiovascular/Cardiometabolic Health. Circ Res. 2023 Apr 28;132(9):1168-1180. Epub 2023 Apr 27.

https://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.123.321565

“Although the full spectrum of cardiovascular and cardiometabolic consequences of e-cig use is not fully appreciated, data is beginning to show that e-cigs can cause both short- and long-term issues on cardiac function, vascular integrity and cardiometabolic issues… A cross-sectional analysis has shown that daily e-cig use was independently associated with higher odds of myocardial infarction (odds ratio, 1.79 [95% CI, 1.20–2.66]), as was daily conventional cigarette smoking (odds ratio, 2.29 [95% CI, 2.29–3.24])… Acute exposures (2 weeks) to e-cigs showed cardiac function changes via echocardiography… [E]-cig effects on the cardiovascular and metabolic outcomes of individuals with comorbidities are of paramount concern when considering the relative and absolute risks of e-cig use in these individuals.”
Stephen Hamann .

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