Association of Electronic Cigarette Use With Incident Respiratory Conditions Among US Adults From 2013 to 2018
Xie W, et al. Association of Electronic Cigarette Use with Incident Respiratory Conditions Among US Adults From 2013 to 2018. JAMA Netw Open. 12 Nov. 2020;3(11):e2020816. “Adjusted for cigarette and other combustible tobacco product use [among 21,618 respondents], demographic characteristics, and chronic health conditions, there was an increased risk of respiratory disease among former e-cigarette users (incidence rate ratio [IRR], 1.28; 95% CI, 1.09-1.50) and current e-cigarette users (IRR, 1.31; 95% CI, 1.08-1.59)… These findings add important evidence on the risk profile of novel tobacco products.”
Introduction
The use of electronic cigarettes (e-cigarettes) has increased dramatically since their introduction to the US market in 2007.1-3 While a 2018 National Academies of Sciences, Engineering, and Medicine report4 found substantial evidence that exposure to toxic substances from e-cigarettes is significantly lower compared with combustible cigarettes, recent studies and case reports suggest that e-cigarettes may present their own unique health risks, including to the respiratory system.5-8 e-Cigarettes are known to contain harmful or potentially harmful constituents, including volatile organic compounds, heavy metals, and ultrafine particles.9-12 e-Cigarette use has been associated with increased airway resistance, impairment of the immune system, and increased cytotoxic effects in the lungs.13-15
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2772829
Stephen Hamann