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Effectiveness of Pharmaceutical Smoking Cessation...

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Effectiveness of Pharmaceutical Smoking Cessation Aids in a Nationally Representative Cohort of American Smokers This study used matching techniques to remove confounding bias in testing population effectiveness of pharmaceutical smoking cessation aids. “Effectiveness of medications to aid quitting among baseline adult smokers who attempted to quit prior to one year

of follow-up in two longitudinal studies in 2002–2003 and 2010–2011 was assessed. There was no evidence that use of varenicline (adjusted risk difference [aRD] = 0.01, 95% confidence interval [CI] = –0.07 to 0.11), bupropion (aRD = 0.02, 95% CI = –0.04 to 0.09), or nicotine replacement (aRD = 0.01, 95% CI = –0.03 to 0.06) increased the probability of 30 days or more smoking abstinence at one-year follow-up. A possible explanation is that counseling and support interventions provided in efficacy trials are rarely delivered in general population cessation attempts.”

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