Gateway or common liability? A systematic review and meta-analysis of studies of adolescent e-cigarette
Gateway or common liability? A systematic review and meta-analysis of studies of adolescent e-cigarette use and future smoking initiation Addiction. 2020 Sep 4. Online ahead of print.Gary C K Chan, Daniel Stjepanovic, Carmen Lim, Tianze Sun, Aathavan Shanmuga Anandan, Jason P Connor, Coral Gartner, Wayne D Hall, Janni Leung | https://onlinelibrary.wiley.com/doi/abs/10.1111/add.15246
“Meta-analysis of 11 studies showed a significant longitudinal association between vaping and smoking (adjusted OR=2.93, 95% CI [2.22,3.87]). Studies with sample sizes<1000 had a significantly higher odds ratio (OR = 6.68, 95% CI [3.63, 12.31]) than studies with sample sizes>1000 (OR = 2.49, 95% CI [1.97,3.15])… Conclusions: There is a longitudinal association between adolescent vaping and smoking initiation; however, the evidence is limited by publication bias, high sample attrition and inadequate adjustment for potential confounders.”
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Stephen Hamann
