Detailed MRI studies show that e-cigarette aerosol inhalation produces endothelial dysfunction which can lead to systemic inflammation and vascular dysfunction
Detailed MRI studies show that e-cigarette aerosol inhalation produces endothelial dysfunction which can lead to systemic inflammation and vascular dysfunction
“Quantitative magnetic resonance imaging (MRI) approaches, developed in the authors’ laboratory, provide conclusive evidence of acute deleterious effects of e-cig aerosol inhalation in the absence of nicotine in tobacco-naïve subjects. Among the pathophysiologic effects observed are transient impairment of endothelial function, vascular reactivity, and oxygen metabolism…. Recent findings from the authors’ laboratories indicate that a single vaping episode involving non-nicotinized e-liquid provoked an inflammatory immune response and oxidative stress along with reduced nitric oxide (NO) bioavailability (Chatterjee et al., 2019b). The latter also manifested in impaired peripheral vascular reactivity and endothelial function as determined by a battery of quantitative magnetic resonance imaging (MRI) metrics (Caporale et al., 2019).”
Wehrli FW, Caporale A, Langham MC, Chatterjee S. New Insights From MRI and Cell Biology Into the Acute Vascular-Metabolic Implications of Electronic Cigarette Vaping. Front Physiol. 2020; 11: 492. Published online 2020 May 21. doi: 10.3389/fphys.2020.00492
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253692/
By Stephen Hamann
